Sickle Cell Anaemia
Sickle cell anaemia is an inherited disorder in which red blood cells carry an abnormal form of haemoglobin. Instead of the flexible disc shape that allows smooth passage through blood vessels, affected cells take on a rigid crescent form that can snag in small vessels, cutting off blood flow. The result is recurring episodes of pain, chronic anaemia, and gradual damage to organs including the spleen, kidneys, and lungs.
Medicine used to treat Sickle Cell Anaemia
Reducing crises with medicine
The main goal of long-term management is to cut the frequency and severity of vaso-occlusive crises, the painful episodes caused by blocked vessels. Hydroxycarbamide (also known as hydroxyurea) is the best-established medicine for this; it raises levels of foetal haemoglobin, which does not sickle, and has been shown to reduce hospital admissions and extend life expectancy. Because sickle cell anaemia sits within the broader field of blood-cancer management, it often appears alongside medicines listed under oncology support.
Staying well-hydrated, avoiding extreme temperature changes, and keeping up with vaccinations (the spleen is often damaged early) are practical steps that complement any medical treatment. Anyone experiencing a sudden severe headache, vision loss, one-sided weakness, or a painful erection lasting more than four hours should seek emergency care immediately.