Understanding Severe Eosinophilic Asthma: Symptoms and Treatments

Severe eosinophilic asthma is a type of asthma marked by high levels of eosinophils, often leading to frequent, severe attacks.
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Health | Respiratory Conditions | Chronic Illness | Eosinophilic Asthma | Severe Asthma Treatment | Eosinophils | Asthma Management
Prepared by Lee Cheng, reviewed by Dr. Helena Rodriguez

Severe Eosinophilic Asthma FAQ


Image credit: slideserve.com

What is eosinophilic asthma?

Eosinophilic asthma (EA) is a type of severe asthma. It’s marked by high levels of white blood cells. These cells, called eosinophils, are a natural part of your body’s immune system. They fight infections and attack invading bacteria.

What are the side effects of eosinophilic asthma?

Severe asthma causes heavy physical, emotional, and social burdens. Your symptoms may be frequent and hard to predict. They can interfere with your daily activities. And the side effects of asthma drugs can be significant. 2,4 Eosinophilic asthma usually starts in adulthood.

Can eosinophilic asthma be fatal?

The disease can even be fatal. Thanks to new treatment options, this does not have to be the case. However, people with eosinophilic asthma must stick to their treatment plan and practice self-care to keep themselves in the best health possible. Eosinophilic asthma is a type of severe asthma.

Where does eosinophilic asthma go?

It goes from your nose and mouth down to the tiniest airways in your lungs. When you have eosinophilic asthma, you have inflammation in your respiratory system caused by cells called eosinophils. Eosinophils are white blood cells. They’re part of your body’s immune system, and normally, they help you fight disease.

What is severe eosinophilic asthma?

This type of asthma is usually associated with adult-onset asthma. Mepolizumab, reslizumab and benralizumab are all biologics that target severe eosinophilic asthma, by reducing eosinophils. Severe asthma with type 2 inflammation where severe asthma symptoms are driven by both allergies and high levels of eosinophils.

What causes eosinophilic asthma?

We do know it is caused by high levels of eosinophils. Eosinophils are a type of white blood cell that helps fight infections. Too many of them can lead to inflammation around the body. 3 In eosinophilic asthma, eosinophil levels are too high in the blood, lungs, and mucus. High eosinophil levels cause the airways to swell and become narrow.

What are eosinophils & how do I know if I have asthma?

Eosinophils are a type of white blood cell linked to inflammation. People with severe asthma sometimes have high levels of eosinophils in the blood. This can be shown with a blood test called an ‘eosinophil count’ which calculates the number of eosinophils in your blood.

Which biologics target severe eosinophilic asthma?

Mepolizumab, reslizumab and benralizumab are all biologics that target severe eosinophilic asthma, by reducing eosinophils. Severe asthma with type 2 inflammation where severe asthma symptoms are driven by both allergies and high levels of eosinophils. Dupilumab is a biologic targeting severe type 2 inflammatory asthma.

Severe Eosinophilic Asthma References

If you want to know more about Severe Eosinophilic Asthma, consider exploring links below:

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