Reslizumab: Intravenous Solution for Eosinophilic Asthma

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What is reslizumab used for?

Reslizumab is used together with other medicines to help control severe asthma in adults. Reslizumab affects your immune system, reducing levels of a certain type of white blood cell that may contribute to the symptoms of asthma. Reslizumab may also be used for purposes not listed in this medication guide.

What is reslizumab antibody?

Reslizumab is a humanized monoclonal antibody against human interleukin-5 (IL-5). Reslizumab binds specifically to IL-5, a key cytokine responsible for the differentiation, maturation, recruitment and activation of human eosinophils.

Is Reslizumab a cytokine?

Reslizumab is an interleukin-5 antagonist (IgG4 kappa). IL-5 is the major cytokine responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils (a cell type associated with inflammation and an important component in the pathogenesis of asthma).

Is Reslizumab a biological medicine?

Reslizumab is a biological medicine. Biological medicines must be prescribed and dispensed by brand name, see Biological medicines and Biosimilar medicines, under Guidance on prescribing; record the brand name and batch number after each administration. For choice of therapy, see Asthma, acute and Asthma, chronic.

How much Reslizumab is in a ML?

The active substance is reslizumab. Each mL of concentrate contains 10 mg of reslizumab (10 mg/mL). Each vial of 2.5 mL contains 25 mg of reslizumab and each vial of 10 mL contains 100 mg of reslizumab. The other excipients are sodium acetate trihydrate, acetic acid glacial, sucrose and water for injections.

How much Reslizumab is in a vial?

Each vial of 2.5 mL contains 25 mg of reslizumab. Each vial of 10 mL contains 100 mg of reslizumab. Reslizumab is a humanised monoclonal antibody produced in mouse myeloma cells (NS0) by recombinant DNA technology. Each vial of 2.5 mL contains 0.05 mmol (1.15 mg) of sodium. Each vial of 10 mL contains 0.20 mmol (4.6 mg) of sodium.

What Is Reslizumab

1. https://en.wikipedia.org/wiki/Reslizumab
2. https://www.drugs.com/mtm/reslizumab.html
3. https://bnf.nice.org.uk/drugs/reslizumab/
4. https://go.drugbank.com/drugs/DB06602
5. https://www.ema.europa.eu/en/medicines/human/EPAR/cinqaero
6. https://www.ncbi.nlm.nih.gov/books/NBK476086/
7. https://www.everydayhealth.com/drugs/reslizumab
8. https://www.medicine.com/drug/reslizumab/hcp