Omalizumab (Xolair) for Asthma and Chronic Urticaria

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What is Xolair ® omalizumab?

Xolair® is a brand of omalizumab. This medication treats allergic asthma, chronic hives and nasal polyps. A healthcare provider will usually give you this injection in a hospital or clinic setting. They can teach you how to administer this medication at home. What is this medication? OMALIZUMAB (oh mah lye ZOO mab) prevents the symptoms of asthma.

Can Omalizumab (Xolair®) be used to treat urticaria?

Omalizumab (Xolair®) as add-on therapy for the treatment of chronic spontaneous urticaria in adult and adolescent (12 years and above) patients with inadequate response to H1-antihistamine treatment (January 2015) There can be variation in the licensing of different medicines containing the same drug.

Does Xolair treat asthma?

IgE levels are increased in people with allergic asthma when they inhale allergens such as pet dander or dust mites which is why Xolair is effective at treating allergic asthma. Xolair will not treat an acute asthma attack or status asthmaticus. 93% of people with moderate-to-severe chronic urticaria have increased total IgE levels.

What is omalizumab used for?

Omalizumab for severe persistent allergic asthma (April 2013) Omalizumab for previously treated chronic spontaneous urticaria (June 2015)

What is Xolair (omalizumab)?

Medically reviewed by Melisa Puckey, BPharm. Last updated on Feb 19, 2024. What is Xolair? Xolair (omalizumab) injection is a medication used to treat types of allergic asthma, nasal polyps and chronic hives (chronic spontaneous urticaria).

Does omalizumab reduce total IgE levels after Xolair treatment?

Total IgE levels did not return to pre-treatment levels for up to one year after discontinuation of XOLAIR. In clinical studies in nasal polyps patients, omalizumab treatment led to a reduction in serum free IgE and an increase in serum total IgE levels, similar to the observations in asthma patients.

How do I report side effects of Xolair?

You may report side effects to FDA at 1-800-FDA-1088. General information about the safe and effective use of XOLAIR. Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. If you would like more information, talk to your healthcare provider or pharmacist.

What Is Omalizumab (Xolair)

1. https://en.wikipedia.org/wiki/Omalizumab
2. https://www.drugs.com/xolair.html
3. https://www.royaldevon.nhs.uk/media/c0wf4don/patient-information-leaflet-omalizumab-xolair-rde-20-207-001.pdf
4. https://bnf.nice.org.uk/drugs/omalizumab/
5. https://www.healthline.com/health/drugs/xolair
6. https://my.clevelandclinic.org/health/drugs/19805-omalizumab-injection
7. https://www.xolair.com/allergic-asthma/about-xolair/how-xolair-may-work.html
8. https://asthma.net/treatment/xolair

Omalizumab (Xolair) Information

1. https://www.ema.europa.eu/en/medicines/human/EPAR/xolair