Dupixent (Dupilumab) for Asthma and Skin Conditions

A monoclonal antibody that inhibits interleukin-4 and interleukin-13 pathway, used for asthma, atopic dermatitis, and CRSwNP.
Category
Drug
Where to get
Prescription only, available at pharmacies.
Prepared by Lee Cheng, reviewed by Dr. Helena Rodriguez

Dupixent (Dupilumab) FAQ


Image credit: farmasmart.com

What is DUPIXENT (dupilumab)?

Dupixent (dupilumab) is a biologic that is given by subcutaneous (under the skin) injection that may be used to treat the following inflammatory conditions:

Does dupilumab (Dupixent®) treat atopic dermatitis?

Dupilumab (Dupixent®) for treatment of moderate-to-severe atopic dermatitis (September 2018)

What is dupilumab used for?

Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis.

Does Dupixent treat eczema?

No, Dupixent is only approved to treat atopic dermatitis (a type of eczema ), asthma, chronic sinusitis with nasal polyps, prurigo nodularis, and eosinophilic esophagitis. To learn about these conditions, see the “ What is Dupixent used for? ” section above.

What is Dupixent used for?

DUPIXENT is indicated as an add-on maintenance treatment in adult patients with inadequately controlled chronic rhinosinusitis with nasal polyposis (CRSwNP). DUPIXENT is indicated for the treatment of adult and pediatric patients aged 1 year and older, weighing at least 15 kg, with eosinophilic esophagitis (EoE).

Is dupilumab safe?

Studies have shown that dupilumab is a well-tolerated treatment. In a 4-year study of the long-term safety of dupilumab, fewer than 1 in 20 patients stopped taking the medication due to side effects. Patients taking dupilumab can commonly develop eye-related side effects.

Are long-term safety results consistent with Dupixent clinical trials?

Long-term safety results for adults continuing on DUPIXENT in the extension study for nearly 5 years were consistent with the adult clinical trials. Use the slider to view these before and after results with 16 weeks of treatment with DUPIXENT. Real patient shown.

Dupixent (Dupilumab) References

If you want to know more about Dupixent (Dupilumab), consider exploring links below:

Explore Related Topics

The Role of Monoclonal Antibodies in Pediatric Asthma Treatment

Discussing the use of monoclonal antibodies in treating severe asthma among children, share your concerns, experiences, or questions.

Monoclonal Antibodies and Asthma: Debunking Myths

There are many myths surrounding the use of monoclonal antibodies in asthma treatment. Let's debunk these myths and spread factual information.

How Immunotherapy for Asthma Fits into Long-term Management Plans

Discuss how immunotherapy integrates with other asthma management plans for long-term control and quality of life improvements. Share tips and strategies.

Understanding the Risks vs. Benefits of Immunotherapy for Asthma

Weigh the risks against the benefits of undergoing immunotherapy for asthma. Share resources, expert opinions, and personal viewpoints to help others make informed decisions.

The Role of Immunotherapy in Childhood Asthma Control

Exploring the benefits and considerations of using immunotherapy for managing asthma in allergic children. Could allergy shots be the shot at relief your child needs?

Who is Eligible for Asthma Immunotherapy?

Explore the criteria that determine whether a patient with asthma is a good candidate for immunotherapy. Discuss the factors that doctors consider before recommending this treatment.