Dupilumab (Dupixent) for Asthma and Dermatitis

An IL-4 and IL-13 inhibitor used for treating atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis.
Category
Drug
Where to get
Prescription required, available in pharmacies and clinics
Active ingredient
Dupilumab
Prepared by Lee Cheng, reviewed by Dr. Helena Rodriguez

Dupilumab (Dupixent) FAQ


Image credit: medscape.com

What is DUPIXENT (dupilumab) used for?

Dupixent (dupilumab) is a prescription drug that’s used to treat certain inflammatory conditions, such as atopic dermatitis (a type of eczema). Dupixent comes as a solution in a prefilled syringe or prefilled pen for injection under the skin. Dupixent is used to treat the following in certain situations:

Does dupilumab (Dupixent®) treat atopic dermatitis?

Dupilumab (Dupixent®) for treatment of moderate-to-severe atopic dermatitis (September 2018)

What is dupilumab used for?

Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis.

Does Dupixent treat eczema?

No, Dupixent is only approved to treat atopic dermatitis (a type of eczema ), asthma, chronic sinusitis with nasal polyps, prurigo nodularis, and eosinophilic esophagitis. To learn about these conditions, see the “ What is Dupixent used for? ” section above.

What is DUPIXENT (dupilumab)?

Dupixent (dupilumab) is a biologic that is given by subcutaneous (under the skin) injection that may be used to treat the following inflammatory conditions:

Is dupilumab safe?

Studies have shown that dupilumab is a well-tolerated treatment. In a 4-year study of the long-term safety of dupilumab, fewer than 1 in 20 patients stopped taking the medication due to side effects. Patients taking dupilumab can commonly develop eye-related side effects.

What is Dupixent used for?

DUPIXENT is indicated as an add-on maintenance treatment in adult patients with inadequately controlled chronic rhinosinusitis with nasal polyposis (CRSwNP). DUPIXENT is indicated for the treatment of adult and pediatric patients aged 1 year and older, weighing at least 15 kg, with eosinophilic esophagitis (EoE).

Dupilumab (Dupixent) References

If you want to know more about Dupilumab (Dupixent), consider exploring links below:

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