Benralizumab: A Solution for Severe Asthma Management

Benralizumab is a monoclonal antibody designed to reduce eosinophils and treat severe asthma.
Category
Drug
Where to get
Prescription only, accessible through healthcare providers
Applicable for
Prepared by Lee Cheng, reviewed by Dr. Helena Rodriguez

Benralizumab FAQ

Who makes benralizumab?

Benralizumab is manufactured under the brand name Fasenra by AstraZeneca AB, Södertälje, Sweden SE-15185. Dávila González I, Moreno Benítez F, Quirce S. Benralizumab: A New Approach for the Treatment of Severe Eosinophilic Asthma.

Is benralizumab a monoclonal antibody?

Benralizumab, sold under the brand name Fasenra, is a monoclonal antibody directed against the alpha chain of the interleukin-5 receptor ( CD125 ). It was developed by MedImmune for the treatment of asthma. Two phase III clinical trials of benralizumab reported meeting their primary endpoints in 2016.

What is the target of benralizumab?

The target of benralizumab is a protein called interleukin-5 receptor, which is found particularly on a type of white blood cell called an eosinophil. What Fasenra is used for Fasenra is used to treat severe eosinophilic asthma in adults. Eosinophilic asthma is a type of asthma where patients have too many eosinophils in the blood or lungs.

What is benralizumab used for?

Benralizumab is a prescription medicine used with other asthma medicines for the maintenance treatment of asthma in people 12 years and older whose asthma is not controlled with their current asthma medicines. Benralizumab helps prevent severe asthma attacks (exacerbations) and may improve your breathing.

What is benralizumab (Fasenra)?

Benralizumab (Fasenra) is a monoclonal antibody used as an add-on therapy to prevent eosinophilic asthma. It is given by subcutaneous injection.

Benralizumab References

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