Xolair (Omalizumab) for Asthma and Urticaria Management

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What is Xolair (omalizumab)?

Medically reviewed by Melisa Puckey, BPharm. Last updated on Feb 19, 2024. What is Xolair? Xolair (omalizumab) injection is a medication used to treat types of allergic asthma, nasal polyps and chronic hives (chronic spontaneous urticaria).

Can Omalizumab (Xolair®) be used to treat urticaria?

Omalizumab (Xolair®) as add-on therapy for the treatment of chronic spontaneous urticaria in adult and adolescent (12 years and above) patients with inadequate response to H1-antihistamine treatment (January 2015) There can be variation in the licensing of different medicines containing the same drug.

Does Xolair treat asthma?

IgE levels are increased in people with allergic asthma when they inhale allergens such as pet dander or dust mites which is why Xolair is effective at treating allergic asthma. Xolair will not treat an acute asthma attack or status asthmaticus. 93% of people with moderate-to-severe chronic urticaria have increased total IgE levels.

What is omalizumab used for?

Omalizumab for severe persistent allergic asthma (April 2013) Omalizumab for previously treated chronic spontaneous urticaria (June 2015)

Is Xolair safe if I am allergic to omalizumab?

IgE contributes to a type of inflammation that plays a key role in causing allergic asthma and chronic rhinosinusitis with nasal polyps. if you are allergic to omalizumab or any of the other ingredients of this medicine (listed in section 6). If you think you may be allergic to any of the ingredients, tell your doctor as you should not use Xolair.

What is Xolair used for?

Xolair is used to improve the control of severe persistent asthma caused by an allergy. It is used as an add-on to asthma treatment in patients from 6 years of age when an antibody called immunoglobulin E (IgE) causes the asthma. Xolair must only be used in patients who:

How is Xolair dose determined?

For patients with asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and IgE-mediated food allergy, dosage determination should be based on the primary diagnosis for which XOLAIR is being prescribed. Adjust doses for significant changes in body weight during treatment.

What Is Xolair (Omalizumab)

1. https://en.wikipedia.org/wiki/Omalizumab
2. https://www.drugs.com/xolair.html
3. https://www.royaldevon.nhs.uk/media/c0wf4don/patient-information-leaflet-omalizumab-xolair-rde-20-207-001.pdf
4. https://bnf.nice.org.uk/drugs/omalizumab/
5. https://www.healthline.com/health/drugs/xolair

Xolair (Omalizumab) Information

1. https://www.ema.europa.eu/en/medicines/human/EPAR/xolair
2. https://www.xolair.com/
3. https://patient-info.co.uk/xolair-69945/patient-leaflet
4. https://www.gene.com/download/pdf/xolair_prescribing.pdf
5. https://www.novartis.com/us-en/sites/novartis_us/files/Xolair_ifu.pdf