Symdeko - Medication for Cystic Fibrosis Treatment

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What is Symdeko?

SYMDEKO is aprescription medicine used for the treatment of cystic fibrosis (CF) in patients age 6 years and older who have two copies of the F508del mutation, or who have at least one mutation in the CF gene that is responsive to treatment with SYMDEKO.

Can Symdeko be used for cystic fibrosis?

SYMDEKO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients age 6 years and older who have two copies of the F508del mutation, or who have at least one mutation in the CF gene that is responsive to treatment with SYMDEKO. Talk to your doctor to learn if you have an indicated CF gene mutation.

Who makes Symdeko?

It’s marketed by Vertex Pharmaceuticals. How does Symdeko work? CF leads to thick mucus building up in the lungs and other organs. Symptoms include breathing difficulties, lung infections, and digestive problems. The condition is caused by mutations in the CFTR gene , which provides the instructions to make the CFTR protein.

How effective is Symdeko?

The effectiveness of SYMDEKO in patients age 6 to less than 12 years was extrapolated from patients age 12 years and older with support from population pharmacokinetic analyses showing similar tezacaftor and ivacaftor exposure levels in patients age 6 to less than 12 years and in patients age 12 years and older [see CLINICAL PHARMACOLOGY ].

How does Symdeko work?

View Important Safety Information and full Prescribing Information, including Patient Information, for SYMDEKO. SYMDEKO is made up of tezacaftor and ivacaftor, which work on certain defects of the CFTR protein at the cellular level. Together, tezacaftor and ivacaftor help certain CFTR proteins work better.

Is Symdeko a tezacaftor?

SYMDEKO is supplied as co-packaged tezacaftor 100 mg/ivacaftor 150 mg fixed-dose combination tablets and ivacaftor 150 mg tablets. Tezacaftor 100 mg/ivacaftor 150 mg tablets are yellow, capsule-shaped, and debossed with “V100” on one side and plain on the other.

What are the side effects of Symdeko?

If you are a child or adolescent, your doctor should perform eye examinations before and during treatment with SYMDEKO to look for cataracts The most common side effects of SYMDEKO include headache, nausea, sinus congestion, and dizziness. These are not all the possible side effects of SYMDEKO.

What Is Symdeko.

1. https://www.symdeko.com/
2. https://www.drugs.com/symdeko.html
3. https://cystic-fibrosis.com/treatment/symdeko
4. https://cysticfibrosisnewstoday.com/symdeko-tezacaftor-ivacaftor-combo-therapy/
5. https://www.medicine.com/drug/symdeko
6. https://www.symdekohcp.com/
7. https://www.rxlist.com/symdeko-drug.htm

Symdeko. Information

1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210491lbl.pdf
2. https://pi.vrtx.com/files/patientpackageinsert_tezacaftor_ivacaftor.pdf
3. https://www.fda.gov/news-events/press-announcements/fda-expands-approval-treatment-cystic-fibrosis-include-patients-ages-6-and-older