Pranlukast: Managing Asthma and COPD

An oral medication used to prevent asthma attacks and manage chronic obstructive pulmonary disease (COPD).

Pranlukast FAQ

What are the side effects of Pranlukast?

Max Kuhn, in Side Effects of Drugs Annual, 2005 The most frequent adverse effects of pranlukast are gastrointestinal, such as abdominal pain and diarrhea in up to 2% and liver injury in up to 0.5% of patients (67 R ). In adults, long-term pranlukast was well tolerated, without significant changes in laboratory parameters (68 c ).

What is Pranlukast used for?

Pranlukast (brand name Onon, オノン) is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co. 's montelukast (Singulair). It is widely used in Japan.

Is Pranlukast a chromone?

N- [4-oxo-2- (2H-tetrazol-5-yl)-1-benzopyran-8-yl]-4- (4-phenylbutoxy)benzamide is a member of chromones. Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.

Is Pranlukast a cysteinyl leukotriene receptor-1 antagonist?

Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. Pranlukast selectively antagonizes leukotriene D 4 (LTD 4) at the cysteinyl leukotriene receptor, CysLT 1, in the human airway.

What does Pranlukast do?

Pranlukast is a selective, competitive antagonist of the cysteinyl leukotrienes, leukotriene (LT) C4, LTD4 and LTE4, antagonising binding at the cysteinyl leukotriene type 1 (CysLTi) receptor.

What are the search terms for Pranlukast?

Search strategy: Medline search terms were ‘pranlukast’ or ‘ONO-1078’ and ‘asthma’. EMBASE search terms were ‘pranlukast’ and ‘asthma’. AdisBase search terms were ‘pranlukast’ or ‘ONO-1078’ and ‘asthma’ and ‘pranlukast’ and ‘PK’ or ‘PD’. Searches were last updated 31 March 2003. Selection: Studies in patients with asthma who received pranlukast.